Before locking in any college football picks on that game or others, be sure to see the latest college football predictions from SportsLine's proven model.

What can sports bettors expect in Week 2 of the college football season? Will Sanders, paired with his son and quarterback Shedeur Sanders, continue to overhaul the traditional norms in college football? Colorado is a 2.5-point home favorite against Nebraska on Saturday in the latest Week 2 college football odds from SportsLine consensus. Week 1 of the 2023 college football season reminded us of how powerful programs remain dominant on a year-to-year basis, but also how quickly things can change, as shown in Deion Sanders' transfer-filled Colorado team knocking off TCU, which reached the national title game last season. Especially in recent seasons with the emergence of the transfer portal, additional eligibility due to the COVID-19 pandemic and incoming recruits getting the opportunity to contribute immediately, it can be hard to keep track of where specific players are from year to year. The early weeks of the college football season can be daunting.